Michele Hummel Selected Research

4- (3- chloro- 5- (1,2- dihydroxyethyl)- 2- pyridyl)- N- (5- (trifluoromethyl)- 2- pyridyl)- 3,6- dihydro- 2H- pyridine- 1- carboxamide

1/2016

A randomized, double-blind, positive-controlled, 3-way cross-over human experimental pain study of a TRPV1 antagonist (V116517) in healthy volunteers and comparison with preclinical profile.

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Michele Hummel Research Topics

Disease

4	Pain (Aches) 09/2017 - 12/2008
3	Hypersensitivity (Allergy) 09/2017 - 09/2010
2	Hyperalgesia 01/2016 - 09/2010
1	Stomach Ulcer (Gastric Ulcer) 09/2017
1	Erythema 01/2016
1	Ulcer 09/2010
1	Inflammation (Inflammations) 09/2009
1	Middle Cerebral Artery Infarction (Middle Cerebral Artery Syndrome) 09/2009
1	Seizures (Absence Seizure) 04/2009
1	Temporal Lobe Epilepsy 04/2009
1	Status Epilepticus (Complex Partial Status Epilepticus) 04/2009
1	Drug Resistant Epilepsy 04/2009
1	Cocaine-Related Disorders (Cocaine Addiction) 04/2002
1	Brain Diseases (Brain Disorder) 04/2002

Drug/Important Bio-Agent (IBA)

3	Morphine (MS Contin)FDA LinkGeneric 09/2017 - 12/2008
2	Indomethacin (Indometacin)FDA LinkGeneric 09/2017 - 09/2010
1	linaclotideIBA 09/2017
1	asimadolineIBA 09/2017
1	3- (4- t- butylphenyl)- N- (2,3- dihydrobenzo(b)(1,4)dioxin- 6- yl)acrylamideIBA 09/2017
1	2- (1,3- dimethyl- 2,6- dioxo- 1,2,3,6- tetrahydro- 7H- purin- 7- yl)- N- (4- isopropylphenyl)acetamideIBA 09/2017
1	Amiloride (Midamor)FDA LinkGeneric 09/2017
1	Opioid Analgesics (Opioids)IBA 09/2017
1	Non-Steroidal Anti-Inflammatory Agents (NSAIDs)IBA 09/2017
1	Carbamazepine (Tegretol)FDA LinkGeneric 09/2017
1	Opioid Receptors (Opioid Receptor)IBA 09/2017
1	SodiumIBA 09/2017
1	Sodium Channel BlockersIBA 09/2017
1	Capsaicin (Zostrix)FDA Link 01/2016
1	Celecoxib (Celebrex)FDA Link 01/2016
1	4- (3- chloro- 5- (1,2- dihydroxyethyl)- 2- pyridyl)- N- (5- (trifluoromethyl)- 2- pyridyl)- 3,6- dihydro- 2H- pyridine- 1- carboxamideIBA 01/2016
1	CP 154526IBA 09/2010
1	SaporinsIBA 09/2010
1	2- methyl- 4- (N- propyl- N- cycloproanemethylamino)- 5- chloro- 6- (2,4,6- trichloranilino)pyrimidineIBA 09/2010
1	CarrageenanIBA 09/2010
1	Adrenocorticotropic Hormone (ACTH)FDA Link 09/2010
1	Atenolol (Tenormin)FDA LinkGeneric 09/2009
1	Evans Blue (Blue, Evans)FDA Link 09/2009
1	Oxycodone (Oxycontin)FDA LinkGeneric 09/2009
1	Pentylenetetrazole (Metrazol)IBA 04/2009
1	Pilocarpine (Ocusert)FDA LinkGeneric 04/2009
1	Anticonvulsants (Antiepileptic Drugs)IBA 04/2009
1	Analgesics (Analgesic Drugs)IBA 12/2008
1	Dopamine Receptors (Dopamine Receptor)IBA 04/2002
1	Neurotransmitter Agents (Neurotransmitter)IBA 04/2002
1	Cocaine (Cocaine HCl)IBA 04/2002

Therapy/Procedure

2	Oral Administration 09/2017 - 09/2010
1	Lasers (Laser) 01/2016